Chronic exposure to high levels of manganese primarily results in problems with the central nervous system. These effects are termed manganism. The symptoms of manganism resemble Parkinson's Disease symptoms.
Manganism occurs when too much manganese injures the part of the brain that controls body movements. This exposure occurs primarily through inhalation. Although some of the symptoms of manganism can be treated with drugs and therapy, the damage that occurs to the brain is permanent.
Manganism symptoms:
Men exposed to high levels may not be able to father children. Other chronic effects from inhaling high amounts of manganese include an increased incidence of cough and bronchitis and susceptibility to infectious lung disease.
Workers usually do not develop symptoms of manganism unless they have been exposed for many months or years. However, there are reports that patients have developed symptoms several years after exposure to manganese had ceased. Manganism is a permanently disabling disease for which there is no cure.